ABCS Organics

Remember, not all CBD oil is the same…
ABSC Pure Organic CBD Oil™ is made from one unique and specific hemp plant with a very distinct and consistent profile of active ingredients. The one-of-a-kind profile in our products was tested to be safe in dogs in the study we sponsored at the highly-respected Colorado State University Veterinary Medical School.

OTHER COMPANY MAKE CLAIMS. WE SPONSOR THE CLINICAL RESEARCH.
ABSC Organics is founded on the importance of science and research.
ABSC Organics believes in our product and in the power of CBD to improve your pet’s wellness and quality of life. But we know there’s a difference between belief and proof—between anecdotal stories and clinical evidence. We care about that difference, and we care about pets. That’s why we’re the only veterinary CBD company who has sponsored three major clinical trials at the nation’s leading veterinary research institution. Want to learn more? We’ve got the ultimate guide to veterinary CBD oil research right here.

CBD OIL FOR DOGS AND CATS—WHAT DOES THE RESEARCH SAY?
Currently, ABSC has sponsored 3 clinical trials at major veterinary research institutions:
- Phase 1 Pharmacokinetics, Safety, and Toxicity Trial at Colorado State University’s College of Veterinary Medicine and Biomedical Sciences: Showed that CBD is most efficiently delivered in the form of oral oil, and that CBD is safe and well tolerated in dogs.1
- Phase 2 Epilepsy Trial at Colorado State University’s College of Veterinary Medicine and Biomedical Sciences: Showed that dogs with idiopathic epilepsy who receive treatment with CBD oil have an 89% reduction in seizure frequency.2
- Phase 2 OsteoarthritisTrial at Colorado State University’s College of Veterinary Medicine and Biomedical Sciences: Results are pending and await publication.4
In addition to these three completed trials, there are many other ongoing trials to determine the safety and efficacy of CBD oil use during chemotherapy in dogs with lymphoma.5
CBD OIL FOR DOGS AND CATS—CLINICAL TRIAL FAQS
It seems like everyone is pushing CBD oil these days. Why haven’t more clinical trials been completed?
CBD shows great promise in treating humans and animals for a diverse array of conditions. And yet, research is limited due to regulatory confusion and questions of legality. Colorado State University’s College of Veterinary Medicine and Biomedical Sciences took an early position that the 2014 Farm Bill legalized CBD as a product of industrial hemp, and began research soon after. Subsequent legislation in 2018 solidified this position, although regulations differ from state to state.
The CBD oil trials look very promising—I want to try CBD with my pet. Can I assume that any CBD oil I buy will give similar results to those seen in the studies?
You absolutely CANNOT assume that all CBD oils on the market will deliver similar results. Some may be full spectrum (includes all components of the cannabis plant, including THC), others may be broad spectrum (includes a broad array of terpenes and cannabinoids, but excludes THC), while still others may be CBD isolate (includes only cannabidiol). In addition, lack of FDA regulation means that unscrupulous operators may be selling product that doesn’t contain the CBD concentration they are advertising. It’s important to choose your brand wisely, look for a Certificate of Analysis, and trust the brand that researchers have trusted for their studies.
The study summaries show that no major or concerning side effects were noted. Did the dogs who participated in the studies experience any side effects?
Like any treatment, CBD can give mild side effects, depending on the pet and the dose. Some dogs in the clinical trials showed minor diarrhea, while others showed slightly elevated alkaline phosphate levels that could be related to treatment. None of these effects were classified as severe or worrisome by the researchers.
ULTIMATE GUIDE TO CBD CLINICAL TRIALS—NOTES, SOURCES AND CITATIONS
- McGrath, S., & Bartner, L.R., & Rao, S., & Kogan, L.R., & Hellyer, P.W. (2018) A Report of Adverse Effects Associated With the Administration of Cannabidiol in Healthy Dogs. Journal of the American Holistic Veterinary Medical Association, Fall 2018, 34-38.
- McGrath, S., & Bartner, L.R., & Rao, S., & Packer, R.A., & Gustafson, D.L. (2018) Randomized Blinded Controlled Clinical Trial to Assess the Effect of Oral Cannabidiol Administration in Addition to Conventional Antiepileptic Treatment on Seizure Frequency in Dogs with Intractable Idiopathic Epilepsy. Journal of the American Veterinary Medical Association, 254(11), 1301-1308.
- Gamble, L., & Boesch, J.M., & Frye, C.W., & Schwark, W.S., & Mann, S., & Wolfe, L., Brown, H., & Berthelsen, E.S., & Wakshlag, J.J. (2018) Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs. Frontiers in Veterinary Science, July 2018 doi: 10.3389/fvets.2018.00165.
- Learn more at http://csu-cvmbs.colostate.edu/vth/veterinarians/clinical-trials/Pages/efficacy-of-cannabidiol-for-the-treatment-of-osteoarthritis-in-dogs.aspx
- Learn more at https://research.vetmed.ufl.edu/clinical-trials/small-animal/a-pilot-study-to-determine-the-safety-and-efficacy-of-cbd-oil-use-during-chemotherapy-in-dogs-with-lymphoma/
- Bartner, L.R., & McGrath, S., & Rao, S., & Hyatt, L.K., & Wittenburg, L.A. (2018) Pharmacokinetics of Cannabidiol Administered by 3 Delivery Methods at 2 Different Dosages to Healthy Dogs. Canadian Journal of Veterinary Research, 2018 (82), 178–183.
- Bartner, L.R., & McGrath, S., & Rao, S., & Hyatt, L.K., & Wittenburg, L.A. (2018) Pharmacokinetics of Cannabidiol Administered by 3 Delivery Methods at 2 Different Dosages to Healthy Dogs. Canadian Journal of Veterinary Research, 2018 (82), 178–183.
- ABSC Organics was previously known as Applied Basic Science Corp. ABSC Pure Organic CBD Oil™ was previously known as C.H.O. Pet Tincture.
- Learn more at https://research.vetmed.ufl.edu/clinical-trials/small-animal/a-pilot-study-to-determine-the-safety-and-efficacy-of-cbd-oil-use-during-chemotherapy-in-dogs-with-lymphoma/
- McGrath, S., & Bartner, L.R., & Rao, S., & Packer, R.A., & Gustafson, D.L. (2018) Randomized Blinded Controlled Clinical Trial to Assess the Effect of Oral Cannabidiol Administration in Addition to Conventional Antiepileptic Treatment on Seizure Frequency in Dogs with Intractable Idiopathic Epilepsy. Journal of the American Veterinary Medical Association, 254(11), 1301-1308.
- Learn more at http://www.akcchf.org/research/participate-in-research/Efficacy-of-cannabidiol-for-the-treatment-of-canine-epilepsy.html
- Gamble, L., & Boesch, J.M., & Frye, C.W., & Schwark, W.S., & Mann, S., & Wolfe, L., Brown, H., & Berthelsen, E.S., & Wakshlag, J.J. (2018) Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs. Frontiers in Veterinary Science, July 2018 doi: 10.3389/fvets.2018.00165.
- Learn more at http://csu-cvmbs.colostate.edu/vth/veterinarians/clinical-trials/Pages/efficacy-of-cannabidiol-for-the-treatment-of-osteoarthritis-in-dogs.aspx

